Unisom® SleepTabs®

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Fall asleep faster and stay asleep longer.

Settle into a great night’s sleep up to 30 minutes faster and stay asleep all night with Unisom® SleepTabs®. Highly effective doxylamine succinate helps get you the rest you need so you can wake up feeling refreshed. That’s why Unisom® is the #1 doctor recommended OTC sleep-aid brand.

  • Full-night sleep
  • Clinically tested, proven effective
  • Non-habit-forming
  • Safe when used as directed
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16-count pack; 32-count pack; 48-count pack; 80-count pack

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Product Information

What is this product / Purpose?

Nighttime sleep-aid

How to use the product


Adults and children 12 years of age and over: take one tablet 30 minutes before going to bed; take once daily or as directed by a doctor.

Children under 12 years of age: do not use.


Do not use in children under 12 years of age
Ask a doctor before use if you have

  • a breathing problem such as asthma, emphysema, or chronic bronchitis
  • glaucoma
  • trouble urinating due to an enlarged prostate gland

Ask a doctor or pharmacist before use if you are taking any other drugs
When using this product

  • avoid alcoholic beverages
  • take only at bedtime

Stop use and ask a doctor if

  • sleeplessness persists continuously for more than two weeks. Insomnia may be a symptom of serious underlying medical illness.

If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Other Information

■ store at 68º-77ºF (20º-25ºC)
■ retain in carton until time of use


A woman blissfully sleeping

Active Ingredient

Doxylamine succinate 25 mg

Unisom® SleepTabs® contain doxylamine succinate, a non-habit-forming antihistamine that makes you sleepy by blocking the effects of histamine in the body, which helps you fall asleep fast and sleep through the night. SleepTabs® are FDA approved, clinically tested, and proven effective.

All Ingredients

Active ingredient: Doxylamine succinate 25 mg

Purpose: Nighttime sleep-aid

Inactive ingredients: anhydrous dibasic calcium phosphate, dibasic calcium phosphate dihydrate, FD&C blue no. 1 aluminum lake, magnesium stearate, microcrystalline cellulose, sodium starch glycolate

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Frequently Asked Questions

  • You may be able to use your HSA and FSA tax-preferred savings account to purchase Unisom® SleepTabs®. The passage of the CARES Act by Congress includes provisions to restore Over the Counter (OTC) eligibility under tax-preferred HSA and FSA accounts. Your plan details may vary, so save your receipt and check with your benefits or health provider for eligibility.

  • Unisom® SleepTabs® active ingredient, doxylamine succinate, is a non-habit forming antihistamine that blocks certain natural substances (histamine, acetylcholine) that your body makes. The lack of histamine causes you to get drowsy and fall asleep quicker. As a result, you’ll get a good night’s sleep from Unisom® tablets.

  • Although the Unisom® SleepTabs® tablet is scored, we do not recommend breaking the tablet for smaller doses. We cannot recommend using this product in any way other than the labeling instructions.

  • For adults 12 years of age and older, 1 tablet should be taken 30 minutes before going to bed, or as directed by a doctor. Do not exceed labeled dosing. Use only as directed.

  • You should speak directly with your healthcare professional before taking any Unisom® products with other sleep medications.

  • Unisom® SleepTabs® can be taken with or without food.

  • Potential side effects may include daytime drowsiness, dry mouth, dizziness, and memory problems. If you experience any of these side effects, discontinue use and consult your doctor. See drug facts on the product packaging for full warning information.

  • Do not use any Unisom® products after the labeled expiration date. Use all products only as directed.

  • If pregnant or breastfeeding, ask a health professional before use.

  • When using Unisom® SleepTabs® avoid alcoholic drinks. Refer to product labeling for complete warnings and directions for use.

  • Unisom® SleepTabs® do not contain any ingredients made from a gluten-containing grain (wheat, barley, or rye).

  • There are no animal-derived ingredients in Unisom® SleepTabs®.

  • Unisom Simple Slumbers® Sleep + Immunity are non-habit-forming and safe when used as directed.

  • Yes, Unisom® SleepTabs® contains doxylamine succinate, which is an antihistamine.

  • Unisom® SleepGels®, SleepMinis®, and SleepMelts® all contain diphenhydramine, while Unisom® SleepTabs® contains a different antihistamine, doxylamine succinate. Like SleepGels®, Minis®, and Melts®, Unisom® PM contains diphenhydramine, but it also contains 200mg of acetaminophen to address minor pain while you sleep. Unisom Simple Slumbers® is drug-free and contains 5 mg of Melatonin, plus passionflower, lemon balm and Vitamin B6. All Unisom® products help you get to sleep faster. Use all products only as directed.

  • No. Your Unisom® nighttime sleep aid is just that: a nighttime sleep aid. Although the active ingredient is an antihistamine, the dosing frequency and directions may differ between its sleep-aid use and the allergy use. Therefore, it is advised you speak to your doctor or healthcare professional regarding allergy symptoms.

  • Unisom® is for occasional sleeplessness only. If your sleeplessness persists for more than two weeks, consult your doctor. Sleeplessness may be a symptom of serious underlying medical illness.

  • Unisom® SleepTabs® help troubled sleepers fall asleep up to 30 minutes faster. However, like any OTC aid, results may vary.

  • Unisom® SleepTabs® help troubled sleepers get a full night's sleep and wake refreshed. However, like any OTC aid, results may vary.

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†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.