Unisom Simple Slumbers® Sleep + Immunity
Get immune support and a better night's sleep with Unisom Simple Slumbers® Sleep + Immunity.
Drug-free melatonin gently works with your natural sleep cycle to help with occasional sleeplessness and gently ease you to sleep.† Because sleep is a time for your body to rest and recover, we added the Unisom® immunity blend — elderberry; zinc; and vitamins C, D, and E — to this sleep solution.
Brought to you by the #1 doctor-recommended OTC sleep-aid brand, Sleep + Immunity helps you fall asleep gently and wake up feeling refreshed, while supporting your immune system.†
- 5 mg of melatonin
- Includes Unisom® immunity blend — elderberry; zinc; and vitamins C, D, and E
- Supports immune system
- Triple-effect melatonin: fall asleep faster, stay asleep longer, wake refreshed†
- Non-habit-forming
- Yummy gummies
Flavors
Elderberry
Sizes
Elderberry: 42-count bottle
Product Information
- Adults 18 years of age and older: Take two gummies before bedtime.
For occasional sleeplessness†
Directions:
Keep out of reach of children.
Consult a health professional if you are experiencing long-term sleep difficulties, if pregnant or breast-feeding, have a medical condition, or taking other medication.
Do not take with alcoholic beverages, while operating machinery, or when driving a vehicle.
Do not use if safety seal is broken.
Store in a cool dry place.
Supplement Facts Serving size: 2 Gummies Serving Per Container: 21 Gummies |
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Amount Per Serving | %DV | |
Calories | 25 | |
Total Carbohydrates |
6 g | 2%** |
Total Sugars | 4 g | ‡ |
Vitamin C (as ascorbic acid) | 135 mg | 150% |
Vitamin D (as cholecalciferol) | 6.3 mcg | 32% |
Vitamin E (as D-alphatocopherol) | 6.7 mg | 45% |
Zinc (as zinc gluconate) | 2.0 mg | 18% |
Sodium | 15.5 mg | < 1% |
Melatonin | 5 mg | ‡ |
Black Elderberry (Sambucus Nigra) Juice Powder |
300 mg | ‡ |
** Daily Percentage Values are based on a 2,000 calorie diet. ‡ Daily Value (DV) not established. |
Ingredients

Supplement Ingredients
- Melatonin (5 mg)
Melatonin is a hormone that is naturally produced in the body to regulate the sleep/wake cycle. It is not a sedative, but a natural cue that it's time to wind down. - Zinc 2.0mg
- Vitamin C 135mg
- Vitamin D 6.3mcg
- Vitamin E 6.7mg
- Zinc and Vitamins C, D, and E are antioxidants that support a healthy immune system.
- Black Elderberry Juice Powder 300mg
Elderberry is a powerful antioxidant shown to support your body's natural defense.
Other Ingredients
Organic tapioca syrup, sugar, water, pectin, citric acid, sodium citrate, carnauba wax, natural flavor
Frequently Asked Questions
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This product is not FSA/HSA eligible. You may be able to use your HSA and FSA tax-preferred savings account to purchase certain over the counter (OTC) products, including Unisom® SleepGels®, Unisom® PM Pain, Unisom® SleepMelts®, Unisom® SleepMinis®, and Unisom® SleepTabs®. The passage of the CARES Act by Congress includes provisions to restore OTC eligibility under tax-preferred HSA and FSA accounts. Your plan details may vary, so save your receipt and check with your benefits or health provider for eligibility.
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Unisom Simple Slumbers® Sleep + Immunity is 100% drug free. It contains 5 mg of melatonin, which provides a triple effect by allowing you to fall asleep fast, sleep soundly, and wake refreshed. Melatonin works naturally with the body to regulate the sleep-wake cycle by physiologically signaling to the body that it is time to sleep — causing drowsiness and lowering body temperature. Melatonin promotes sleep in a way that resembles the natural onset of sleep — through quiet wakefulness to the sleeping state, while maintaining normal sleep cycle. By providing 5 mg of melatonin, Unisom® Simple Slumbers™ supplements the body’s natural sleep process to help you fall asleep.† It also contains elderberry, a powerful antioxidant, traditionally used to help support your natural defenses. It also contains zinc and vitamins C, D, and E to support a healthy immune system.
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For adults and children 18 years of age or older, 2 gummies should be taken before bedtime, or as directed by a doctor. Do not exceed labeled dosing. Use only as directed.
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You should speak directly with your healthcare professional before taking any Unisom® products with other sleep medications.
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Unisom Simple Slumbers® Sleep + Immunity should be taken 30-60 mins before bedtime, after food or without food.
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Potential side effects may include headaches and daytime sleepiness. If you experience any of these side effects, discontinue use and consult your doctor.
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Do not use any Unisom® products after the labeled expiration date. Use all products only as directed.
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If pregnant or breastfeeding, ask a health professional before use.
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While taking Unisom Simple Slumbers® Sleep + Immunity, avoid alcoholic drinks. Refer to product labeling for complete warnings and directions for use.
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Unisom Simple Slumbers® Sleep + Immunity is gluten free.
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Unisom Simple Slumbers® is a sleep supplement that contains melatonin which should not cause tolerance when used as directed.
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Unisom Simple Slumbers® Sleep + Immunity is a sleep supplement that contains melatonin, which should not cause tolerance when used as directed.
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Unisom Simple Slumbers® Sleep + Immunity are non-habit-forming and safe when used as directed.
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No, Unisom Simple Slumbers® Sleep + Immunity is a dietary supplement and does not contain an antihistamine. They're a combination of melatonin, zinc, vitamins C, D, E, and elderberry.
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Unisom® SleepGels®, SleepMinis®, and SleepMelts® all contain diphenhydramine, while Unisom® SleepTabs® contains a different antihistamine, doxylamine succinate. Like SleepGels®, SleepMinis®, and SleepMelts®, Unisom® PM Pain contains diphenhydramine, but it also contains 325 mg of acetaminophen to address minor pain while you sleep. Unisom® Simple Slumbers™ is drug-free, and contains 5 mg of melatonin, plus passionflower, lemon balm, and vitamin B6. All Unisom® products help you get to sleep faster. Unisom Simple Slumbers® Sleep + Immunity contains 5 mg of melatonin plus powerful antioxidants that help support a healthy immune system. Use all products only as directed.
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No. Your Unisom Simple Slumbers® nighttime sleep supplement is just that: a nighttime sleep supplement. It is advised you speak to your doctor or healthcare professional regarding allergy symptoms.
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Unisom Simple Slumbers® Sleep + Immunity is drug free and non-habit-forming. It can be taken as needed for occasional sleeplessness. Consult a health professional if you are experiencing long-term sleep difficulties.
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Unisom Simple Slumbers® Sleep + Immunity helps with occasional sleeplessness so you fall asleep faster. However, results may vary.
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Unisom Simple Slumbers® Sleep + Immunity helps occasionally troubled sleepers wake up less and sleep soundly, naturally. However, like any sleep supplement, results may vary.
Learn more about sleep and sleeplessness.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.