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Unisom SleepMelts

Melt Away Your Restless Nights

Unisom SleepMeltsTM are great tasting sleep aids that dissolve on your tongue in just 30 seconds – no water required.1

Unisom SleepMelts contain the #1 Pharmacist Recommended Sleep-Aid Ingredient,2 which helps you catch some ZZZ’s and wake up refreshed.

It’s safe, non-habit forming and has a great cherry flavor.

  • Dissolves In 30 seconds
  • #1 Pharmacist
  • Cherry

What Is Diphenhydramine HCl?

Diphenhydramine HCl, the #1 Pharmacist Recommended Sleep Aid Ingredient,2 is a non-habit forming antihistamine that helps you get a safe, restful night’s sleep. It works by blocking the effects of a naturally occurring neurotransmitter your body makes called histamine.3 When histamine is reduced, you experience drowsiness, which allows you to fall asleep faster and stay asleep longer.

Active ingredient
(in each tablet)

Diphenhydramine HCl 25 mg 


 Nighttime sleep-aid


  • for relief of occasional sleeplessness


Do not use:

  • for children under 12 years of age
  • with any other product containing diphenhydramine, even one used on skin

Ask a doctor  before use if you have:

  • a breathing problem such as emphysema or chronic bronchitis
  • glaucoma
  • trouble urinating due to an enlarged prostate gland

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers

When using this product avoid alcoholic drinks

Drug Facts (continued)

Stop use and ask a doctor if sleeplessness persists continuously for more than two weeks. Insomnia may be a symptom of serious underlying medical illness.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.


  • adults and children 12 years and older: 2 tablets (25 mg each) at bedtime if needed, or as directed by doctor
  • place 2 tablets on tongue; tablets dissolve with or without water
  • allow tablets to dissolve in mouth or chew before swallowing

Inactive ingredients

citric acid, ethylcellulose, flavor, hydroxypropyl cellulose, mannitol, microcrystalline cellulose, PVP, red 7, starch, sucralose, sucrose (245-236)


1 Speed of dissolution doesn’t necessarily correlate with onset of sleep
2 Pharmacy Times – OTC Survey, 2015

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